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Their findings provide new insight into the role of these cells in the autoimmune disease multiple sclerosis (MS). The new indicators are set to be an important ...www.sciencecodex.com/going_live_immune_cell_activation_i...

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PhilaU Students Will Bike from Maine to Florida for Multiple Sclerosis Research. Posted on May 16, 2013. Philadelphia University architecture students Cameron ...wordpress.philau.edu/.../philau-students-will-bike-from-maine...

The parking lot at the Whizin's Market Square was packed with motorcycle enthusiasts Sunday afternoon for radio host Peter Tilden's (ABC TalkRadio 790.agourahills.patch.com/.../talk-radio-host-ride-for-multiple-scle...

Fore Pharma's latest report Global Multiple Sclerosis Pipeline Capsule - 2013' provides up-to-date information on key Research and Development (R&D) ...www.businesswire.com/.../Research-Markets-Global-Multiple-...

The Swedish Multiple Sclerosis Center Art Show is accepting entries for its 4th annual exhibit. Art will be displayed July 6-7 at the Seattle Center Armory.www.swedish.org/.../Swedish-Multiple-Sclerosis-Center-Blog

( Max-Planck-Gesellschaft ) Scientists from the Max Planck Institute of Neurobiology in Martinsried have now presented not one, but two studies introducing new indicator molecules which can visualize the activation of T cells. Their findings provide new insight into the role of these cells in the autoimmune disease multiple sclerosis. The new indicators are set to be an important tool in the ...

Young people with MS are taking the lead and sharing the mottos that guide their lives

NEW YORK, May 24, 2013 /PRNewswire-USNewswire/ -- Multiple sclerosis is a life altering disease that affects each person in a unique and different way. More than 2.1 million people worldwide live with MS, which is why demonstrating the power and ...See all stories on this topic »

On June 15, 2013, the second annual Multiple Sclerosis Walk will be held at the Butternut School. Registration starts at 8:30 a.m. and the walk begins at 9:30 a.m.. The cost of the walk is $15 for adults and $10 for children (children under 10 years ...See all stories on this topic »

ziMS Foundation, Zimmerman's personal charity, is dedicated to the treatment and ultimate cure of Multiple Sclerosis by funding comprehensive support and educational programs. To that end, Zimmerman presented $70,000 worth of donations to the multiple ...See all stories on this topic »Washington Times (blog)

Klein approached the construction crews after Dave Schultz, 49, a Harrison high-rise resident who has multiple sclerosis, was knocked over when a tractor-trailer clipped his motorized wheelchair. Schultz suffered a broken ankle in the April 22 accident.See all stories on this topic »

3X a week glatiramer acetate (Copaxone); innovation or life-cycle management? #MSBlog #MSResearch Epub: Khan et al. Three times weekly glatiramer acetate in relapsing-remitting multiple sclerosis. Ann Neurol. 2013 May 20. doi: 10.1002/ana.23938. Objective: To assess the efficacy and safety of glatiramer acetate (GA) 40 mg administered three times weekly (tiw) compared with placebo in RRMSers.  Methods: This randomized, double-blind study was conducted in 142 sites in 17 countries. RRMSers with at least one documented relapse in the 12 months before screening, or at least two documented relapses in the 24 months before screening, and an Expanded Disability Status Scale score ≤5.5, were randomized 2:1 to receive either subcutaneous (sc) GA 40 mg tiw (1 mL) or placebo for 12 months.  Results: Of 1524 MSers screened, 1404 were randomized to receive GA 40 mg sc tiw (n=943) or placebo (n=461). Ninety-three percent and 91% of MSers in the placebo and GA groups, respectively,... [[ This is a content summary only. Visit my website for full links, other content, and more! ]]

Epub: Mierzwa et al. FGF2 and FGFR1 Signaling Regulate Functional Recovery Following Cuprizone Demyelination Neurosci Lett. 2013. doi:pii: S0304-3940(13)00430-8. 10.1016/j.neulet.2013.05.010.  In demyelinating diseases, such as multiple sclerosis, remyelination offers the potential to recover function of viable denuded axons by restoring saltatory conduction and/or protecting from further damage. Mice with genetic reduction of fibroblast growth factor 2 (Fgf2) or Fgf receptor 1 (Fgfr1) exhibit dramatically improved remyelination following experimental demyelination with cuprizone. The current studies are the first to test neurobehavioral outcomes with these gene deletions that improved remyelination. The cuprizone protocols used did not produce overt abnormalities but did reduce bilateral sensorimotor coordination (complex wheel task) and increase sociability (two chamber apparatus with novel mouse). A significant effect of genotype was observed on the complex wheel... [[ This is a content summary only. Visit my website for full links, other content, and more! ]]

Epub: Kinnunen et al. Specific peripheral B cell tolerance defects in patients with multiple sclerosis. J Clin Invest. 2013. doi:pii: 68775. 10.1172/JCI68775. Multiple sclerosis (MS) is a genetically mediated autoimmune disease of the central nervous system. B cells have recently emerged as major contributors to disease pathogenesis, but the mechanisms responsible for the loss of B cell tolerance in patients with MS are largely unknown. In healthy individuals, developing autoreactive B cells are removed from the repertoire at 2 tolerance checkpoints during early B cell development. Both of these central and peripheral B cell tolerance checkpoints are defective in patients with rheumatoid arthritis (RA) and type 1 diabetes (T1D). Here, we found that only the peripheral, but not the central, B cell tolerance checkpoint is defective in patients with MS. We show that this specific defect is accompanied by increased activation and homeostatic proliferation of mature naive B cells.... [[ This is a content summary only. Visit my website for full links, other content, and more! ]]

Live MS Twitter Chat: Tuesday May 29th, 6pm UK Summer Time or 1 pm EST #HealthTalk #MSBlog "I have volunteered to do a Twitter Chat to honor World MS Day next week. This is a live Q&A session via Twitter. Although I tweet daily and use Twitter all the time this will be my first live event. You are welcome to sign in to and participate. To participate you will need your own Twitter account. To follow the Chatter it is best to use TweetChat (www.tweetchat.com), a site dedicated to live Twitter conversations, or TweetDeck (www.tweetdeck.com); both these sites allow you track conversations using the # (hashtag). Next Tuesday the hashtag that will be used is #HealthTalk" For more information check out the Healthtalk site:  In honor of World MS Day on May 29th, Everyday Health will co-host a live Twitter chat on Tuesday, May 28 at 6pm UK Summer Time or 1 pm EST, with experts from the National Multiple Sclerosis Society, plus other guests affiliated with the Society. Bruce... [[ This is a content summary only. Visit my website for full links, other content, and more! ]]

Research and Markets has announced the addition of the "Global Multiple Sclerosis Pipeline Capsule - 2013" repor

Research and Markets has announced the addition of the "Daclizumab - Forecast and Market Analysi

Research and Markets has announced the addition of the "Siponimod - Forecast and Market Analysis

Multiple sclerosis is characterized by central nervous system lesions causing neurologic dysfunction and other conditions, such as fatigue, pain, depression, and ...www.aafp.org/afp/2013/0515/p712.html